Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14183743 | 1.00 | APP (0.38) | APPCYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14212183 | 0.97 | ALDH1A1 (0.38) | APPCYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14212165 | 0.92 | CYP1A2 (0.46) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14183710 | 0.92 | CYP2C19 (0.43) | APPCYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9811530 | 0.92 | CYP2C19 (0.43) | APPCYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14463256 | 0.92 | CYP2C19 (0.43) | APPCYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14073249 | 0.92 | ALDH1A1 (0.41) | APPCYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14212170 | 0.90 | METAP1 (0.40) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL26550589 | 0.90 | CYP2C19 (0.36) | APPCYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14183683 | 0.89 | CYP2C19 (0.41) | APPCYP2C19CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8679644-B2 | Electroluminescent polymers containing planar arylamine units, the preparation and use thereof | MERCK PATENT GMBH (DE) | 2014-03-25 | — | — | US | disclosed |