Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.44 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.44 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.44 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.44 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156210 | 1.00 | POLB (0.47) | POLBEPHX2APPATMSNCA | |
| SCHEMBL27856162 | 1.00 | POLB (0.47) | POLBEPHX2APPATMSNCA | |
| SCHEMBL152729 | 0.90 | SLC28A3 (0.51) | EPHX2ATMSNCASLC28A3SLC5A1 | |
| SCHEMBL152730 | 0.90 | SLC28A3 (0.51) | EPHX2ATMSNCASLC28A3SLC5A1 | |
| SCHEMBL153741 | 0.90 | KMT2A (0.43) | POLBEPHX2APPSNCASLC28A3 | |
| SCHEMBL27856154 | 0.90 | KMT2A (0.43) | POLBEPHX2APPSNCASLC28A3 | |
| SCHEMBL153742 | 0.90 | KMT2A (0.43) | POLBEPHX2APPSNCASLC28A3 | |
| SCHEMBL156208 | 0.89 | NR4A2 (0.43) | POLBAPPLGALS9LGALS1LGALS3 | |
| SCHEMBL153288 | 0.86 | ATM (0.45) | EPHX2ATMSLC28A3SLC5A1SLC5A2 | |
| SCHEMBL153289 | 0.86 | ATM (0.45) | EPHX2ATMSLC28A3SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |