Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA3 | P07451 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561280 | 0.88 | CA9 (0.53) | MAOBCA9MEN1KMT2ANPC1 | |
| SCHEMBL1562291 | 0.83 | MAOB (0.60) | MAOBCA9MEN1KMT2ANPC1 | |
| SCHEMBL23796860 | 0.77 | MEN1 (0.65) | MAOBMEN1KMT2ASLC16A3KDM4E | |
| SCHEMBL27862583 | 0.75 | MEN1 (0.58) | MAOBMEN1KMT2ASLC16A3KDM4E | |
| SCHEMBL3592957 | 0.74 | MAOB (0.81) | MAOBCA9MEN1KMT2ANPC1 | |
| SCHEMBL27489408 | 0.73 | MEN1 (0.63) | MAOBMEN1KMT2ASLC16A3MCL1 | |
| 7-Benzyloxycoumarin SCHEMBL29365449 | 0.72 | MAOB (1.00) | MAOBCA9MEN1KMT2ANPC1 | |
| 7-Benzyloxycoumarin SCHEMBL3901170 | 0.72 | MAOB (1.00) | MAOBCA9MEN1KMT2ANPC1 | |
| SCHEMBL343794 | 0.72 | MCL1 (0.78) | MAOBMEN1KMT2AMAOASLC16A3 | |
| SCHEMBL4992573 | 0.72 | MEN1 (0.47) | MAOBMEN1KMT2ANPC1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805160-B1 | SUBSTITUTED BENZOPYRANS AS SELECTIVE ESTROGEN RECEPTOR-BETA AGONISTS | LILLY CO ELI (US) | 2011-04-06 | — | — | EP | disclosed |
| US-7354951-B2 | Substituted benzopyrans as selective estrogen receptor-beta agonists | ELI LILLY AND COMPANY (US) | 2008-04-08 | — | — | US | disclosed |
| US-20080064742-A1 | Substituted Benzopyrans as Selective Estrogen Receptor-Beta Agonists | ELI LILLY AND COMPANY | 2008-03-13 | — | — | US | disclosed |
| EP-1805160-A1 | SUBSTITUTED BENZOPYRANS AS SELECTIVE ESTROGEN RECEPTOR-BETA AGONISTS | ELI LILLY AND COMPANY (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006044176-A1 | SUBSTITUTED BENZOPYRANS AS SELECTIVE ESTROGEN RECEPTOR-BETA AGONISTS | ELI LILLY AND COMPANY (US) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064742-A1 | Substituted Benzopyrans as Selective Estrogen Receptor-Beta Agonists | ESR2, GPER1, ESR1 | MAOB 1276/4885CA9 3318/4885MEN1 2888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.