SCHEMBL156239

SCHEMBL156239

[NH]c1ccc2c(O)ccc(S(=O)(=O)O)c2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNNI3 P19429 1/20 0.51
TNNT2 P45379 1/20 0.51
TNNC1 P63316 1/20 0.51
HKDC1 Q2TB90 1/20 0.51
COMT P21964 1/20 0.42
LDHA P00338 1/20 0.42
AURKA O14965 1/20 0.39
AURKB Q96GD4 1/20 0.39
MPL P40238 4/20 0.37
NT5E P21589 1/20 0.37
HSD17B10 Q99714 2/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
HIF1A Q16665 1/20 0.36
CYP1A2 P05177 1/20 0.36
EGFR P00533 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CDK2 P24941 1/20 0.34
CTRC Q99895 1/20 0.34
TTR P02766 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158792 0.83 COMT (0.41) TNNI3TNNT2TNNC1HKDC1COMT
SCHEMBL8113889 0.80 TNNI3 (0.53) TNNI3TNNT2TNNC1HKDC1COMT
SCHEMBL8020884 0.79 HSD17B10 (0.49) TNNI3TNNT2TNNC1HKDC1COMT
SCHEMBL156240 0.79 NT5E (0.54) TNNI3TNNT2TNNC1HKDC1COMT
SCHEMBL28205084 0.79 TNNI3 (0.51) TNNI3TNNT2TNNC1HKDC1COMT
SCHEMBL28205085 0.79 TNNI3 (0.51) TNNI3TNNT2TNNC1HKDC1COMT
SCHEMBL29564390 0.75 LDHA (0.70) TNNI3TNNT2TNNC1HKDC1COMT
SCHEMBL249254 0.75 LDHA (0.70) TNNI3TNNT2TNNC1HKDC1COMT
SCHEMBL10629458 0.75 TNNI3 (0.58) TNNI3TNNT2TNNC1HKDC1NT5E
SCHEMBL11837949 0.75 TNNI3 (0.67) TNNI3TNNT2TNNC1HKDC1COMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120056931-A1 MAGENTA COLORING MATTER, INK COMPOSITION, AND COLORED BODY NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-03-08 US disclosed