Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL802249 | 0.87 | GAA (0.39) | GAACYP2C19POLBLMNACYP3A4 | |
| SCHEMBL17373247 | 0.85 | GAA (0.35) | GAACYP2C19POLBLMNACYP3A4 | |
| SCHEMBL22067477 | 0.84 | GAA (0.37) | GAACYP2C19POLBLMNACYP3A4 | |
| SCHEMBL12060404 | 0.81 | GAA (0.38) | GAACYP2C19POLBLMNACYP3A4 | |
| SCHEMBL13868035 | 0.81 | GAA (0.38) | GAACYP2C19POLBLMNACYP3A4 | |
| SCHEMBL3329152 | 0.77 | CYP2C19 (0.43) | GAACYP2C19POLBLMNACYP3A4 | |
| SCHEMBL5423132 | 0.77 | HTR2A (0.36) | GAACYP2C19POLBLMNACYP3A4 | |
| SCHEMBL14923156 | 0.77 | LRRK2 (0.44) | GAACYP2C19POLBCYP3A4PDE3B | |
| SCHEMBL21379850 | 0.76 | LRRK2 (0.37) | GAALMNACYP1A2LRRK2HTR2A | |
| SCHEMBL2611115 | 0.76 | GAA (0.40) | GAACYP2C19POLBLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398778-B1 | AMINOPYRIDINEAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-03-26 | — | — | EP | disclosed |