Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966796 | 0.76 | ATM (0.49) | ADORA1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL1967026 | 0.75 | ATM (0.46) | ADORA1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL1965492 | 0.73 | NR1H4 (0.54) | ADORA1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL13464227 | 0.73 | ALDH1A1 (0.62) | ADORA1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL1965345 | 0.72 | ALDH1A1 (0.64) | ADORA1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL1966324 | 0.72 | CREBBP (0.41) | ADORA1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL13464311 | 0.70 | ALDH1A1 (0.64) | ADORA1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL1970285 | 0.70 | ALDH1A1 (0.64) | ADORA1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL1967815 | 0.70 | ALDH1A1 (0.64) | ADORA1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL15623984 | 0.66 | KDM4E (0.35) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334675-B1 | IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS | CSIR (ZA) | 2014-03-26 | — | — | EP | disclosed |