Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 6/20 | 0.81 |
| ▸ | TUBB | P07437 | 6/20 | 0.81 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.81 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.81 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.81 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.81 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.81 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.81 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.81 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.81 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.81 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.81 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.81 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.81 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.81 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.68 |
| ▸ | BRD4 | O60885 | 1/20 | 0.63 |
| ▸ | TRIM33 | Q9UPN9 | 3/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | PKLR | P30613 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964838 | 0.90 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2995123 | 0.86 | TUBB4A (0.93) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28713723 | 0.86 | TUBB4A (0.93) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1967297 | 0.82 | TUBB4A (0.84) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL18313563 | 0.82 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL18313625 | 0.82 | TUBB4A (0.79) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1969357 | 0.78 | TUBB4A (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16416672 | 0.78 | BRD4 (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27101605 | 0.77 | TRIM33 (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1968349 | 0.77 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334675-B1 | IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS | CSIR (ZA) | 2014-03-26 | — | — | EP | disclosed |