SCHEMBL15624647

SCHEMBL15624647

Cc1c([N+](=O)[O-])c(C)c2nsnc2c1C

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.44
▸ TDP1 Q9NUW8 2/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ TXNRD1 Q16881 3/20 0.38
▸ TXNRD3 Q86VQ6 3/20 0.38
▸ TXNRD2 Q9NNW7 3/20 0.38
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ PTPN11 Q06124 1/20 0.33
▸ PKM P14618 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ THRB P10828 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14123560 0.91 MAPT (0.46) MAPTTDP1ALDH1A1TXNRD1TXNRD3
SCHEMBL7592620 0.76 TDP1 (0.50) TDP1ALDH1A1MEN1KMT2APKM
SCHEMBL15624662 0.75 KMT2A (0.43) MAPTTDP1ALDH1A1MEN1KMT2A
SCHEMBL18217202 0.75 MAPT (0.41) MAPTTDP1ALDH1A1TXNRD1TXNRD3
SCHEMBL3816541 0.74 TDP1 (0.48) TDP1ALDH1A1MEN1KMT2APKM
SCHEMBL21938642 0.73 MAPT (0.35) MAPTTDP1MEN1KMT2A
SCHEMBL17660029 0.72 MAPT (0.42) MAPTALDH1A1SMN1; SMN2THRBHPGD
SCHEMBL4927428 0.71 TDP1 (0.50) TDP1ALDH1A1MEN1KMT2APKM
SCHEMBL862824 0.71 MEN1 (0.36) MAPTMEN1KMT2A
SCHEMBL3619569 0.71 MAPT (0.44) MAPTTDP1ALDH1A1TXNRD1TXNRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180053868-A1 PHOTOELECTRIC CONVERSION DEVICE HAVING REFLECTION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-22 — — US disclosed
US-20170162808-A1 PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 — — US disclosed
US-20170162808-A1 PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 — — US disclosed
US-9512149-B2 Reactive compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-06 — — US disclosed
US-9512149-B2 Reactive compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-06 — — US disclosed
US-9396831-B2 Polymer compound and electronic device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-19 — — US disclosed
US-9396831-B2 Polymer compound and electronic device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-19 — — US disclosed
US-20150353583-A1 REACTIVE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-10 — — US disclosed
US-20150353583-A1 REACTIVE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-10 — — US disclosed
US-20140084217-A1 POLYMER COMPOUND AND ELECTRONIC DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-03-27 — — US disclosed
US-20140084217-A1 POLYMER COMPOUND AND ELECTRONIC DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-03-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150353583-A1 REACTIVE COMPOUND AR, AHR, ROS1 MAPT 2942/4885TDP1 3640/4885ALDH1A1 1371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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