SCHEMBL156276

SCHEMBL156276

NCc1cccc(I)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29439586 1.00
Hydrochloric Acid SCHEMBL30732660 0.98 IDO1 (0.61)
Hydrochloric Acid SCHEMBL302630 0.98 IDO1 (0.61)
SCHEMBL28262995 0.91 IDO1 (0.52)
SCHEMBL10526693 0.84
SCHEMBL923008 0.82 IDO1 (0.47)
SCHEMBL171704 0.81 TAAR1 (0.57)
SCHEMBL10422276 0.81 LOXL2 (0.71)
SCHEMBL36008 0.81 LOXL2 (0.71)
SCHEMBL9352538 0.79 IDO1 (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 810 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12187811-B2 Cyclic peptide compound simulating natural product structure, and method for preparation thereof NANKAI UNIVERSITY (CN) 2025-01-07 US claimed
CN-113687006-B Method for detecting content of m-iodobenzyl guanidine by adopting high performance liquid chromatography 原子高科股份有限公司 2023-05-12 CN claimed
US-20220315623-A1 Cyclic Peptide Compound Simulating Natural Product Structure, And Method For Preparation Thereof NANKAI UNIVERSITY (CN) 2022-10-06 US claimed
CN-113687006-A Method for detecting content of m-iodobenzylguanidine by adopting high performance liquid chromatography 原子高科股份有限公司 2021-11-23 CN claimed
EP-3888694-A1 PREPARATIONS OF META-IODOBENZYLGUANIDINE AND PRECURSORS THEREOF Molecular Insight Pharmaceuticals, Inc. (US) 2021-10-06 EP claimed
EP-3268052-B1 PREPARATIONS OF META-IODOBENZYLGUANIDINE AND PRECURSORS THEREOF MOLECULAR INSIGHT PHARM INC (US) 2021-06-23 EP claimed
CN-110183513-B Cyclopeptide compound simulating structure of natural product and preparation method thereof 南开大学 2021-04-27 CN claimed
WO-2020228097-A1 CYCLIC PEPTIDE COMPOUND SIMULATING NATURAL PRODUCT STRUCTURE, AND METHOD FOR PREPARATION THEREOF 南开大学 2020-11-19 WO claimed
US-9833768-B2 Affinity reagents for protein purification IMPOSSIBLE FOODS INC. (US) 2017-12-05 US claimed
US-20170320041-A1 AFFINITY REAGENTS FOR PROTEIN PURIFICATION IMPOSSIBLE FOODS INC. 2017-11-09 US claimed
US-20100087636-A1 PROCESS FOR THE SYNTHESIS OF IB-MECA CAN-FITE BIOPHARMA LTD. (IL) 2010-04-08 US claimed
EP-1451160-B1 PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN ICAGEN INC (US) 2010-01-13 EP claimed
EP-2137202-A1 PROCESS FOR THE SYNTHESIS OF IB-MECA Can-Fite Biopharma Ltd. (IL) 2009-12-30 EP claimed
EP-1723140-B1 PROCESS FOR THE PREPARATION OF TRYPTASE INHIBITORS AVENTIS PHARMA INC (US) 2009-11-04 EP claimed
WO-2008111082-A1 PROCESS FOR THE SYNTHESIS OF IB-MECA CAN-FITE BIOPHARMA LTD. (IL) 2008-09-18 WO claimed
EP-1963344-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2008-09-03 EP claimed
US-20070275986-A1 Use of purine derivatives for the production of medicaments for the treatment of mucoviscidosis and diseases related to protein addressing errors in cells CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2007-11-29 US claimed
EP-1802310-A1 USE OF PURINE DERIVATIVES FOR THE PRODUCTION OF MEDICAMENTS FOR THE TREATMENT OF MUCOVISCIDOSIS AND DISEASES RELATED TO PROTEIN ADDRESSING ERRORS IN CELLS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2007-07-04 EP claimed
WO-2007071453-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2007-06-28 WO claimed
WO-2006042949-A1 USE OF PURINE DERIVATIVES FOR THE PRODUCTION OF MEDICAMENTS FOR THE TREATMENT OF MUCOVISCIDOSIS AND DISEASES RELATED TO PROTEIN ADDRESSING ERRORS IN CELLS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2006-04-27 WO claimed