Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1562893 | 0.89 | CXCR2 (0.79) | CXCR2 | |
| SCHEMBL1562925 | 0.88 | CXCR2 (1.00) | CXCR2 | |
| Hydrochloric Acid SCHEMBL4355911 | 0.87 | CXCR2 (0.98) | CXCR2 | |
| SCHEMBL13096283 | 0.85 | CXCR2 (0.79) | CXCR2 | |
| Elubrixin SCHEMBL30515706 | 0.84 | CXCR2 (1.00) | CXCR2 | |
| Elubrixin SCHEMBL1562280 | 0.84 | CXCR2 (1.00) | CXCR2 | |
| Elubrixin SCHEMBL1741720 | 0.83 | CXCR2 (0.98) | CXCR2 | |
| SCHEMBL4616300 | 0.83 | CXCR2 (0.78) | CXCR2 | |
| SCHEMBL4162988 | 0.81 | CXCR2 (0.84) | CXCR2 | |
| SCHEMBL1562600 | 0.80 | CXCR2 (0.74) | CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2388006-A1 | Urea derivatives as IL-8 receptor antagonists | GlaxoSmithKline LLC (US) | 2011-11-23 | — | — | EP | claimed |
| US-20110253866-A1 | SWINGING SUPPORT DEVICE | PANASONIC CORPORATION (JP) | 2011-10-20 | — | — | US | claimed |
| EP-1558259-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2009-04-08 | — | — | EP | claimed |
| US-20060040952-A1 | Il-8 receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2006-02-23 | — | — | US | claimed |
| EP-1558259-A2 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-08-03 | — | — | EP | claimed |
| WO-2004039775-A2 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-13 | — | — | WO | claimed |
| EP-2388006-A1 | Urea derivatives as IL-8 receptor antagonists | GlaxoSmithKline LLC (US) | 2011-11-23 | — | — | EP | disclosed |
| US-20110253866-A1 | SWINGING SUPPORT DEVICE | PANASONIC CORPORATION (JP) | 2011-10-20 | — | — | US | disclosed |
| EP-1558259-B1 | Urea derivatives as IL-8 receptor antagonists | GLAXOSMITHKLINE LLC (US) | 2011-04-06 | — | — | EP | disclosed |
| US-7709485-B2 | IL-8 receptor antagonists | GLAXOSMITHKLINE LLC (US) | 2010-05-04 | — | — | US | disclosed |
| US-20090093492-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION | 2009-04-09 | — | — | US | disclosed |
| EP-1558259-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2009-04-08 | — | — | EP | disclosed |
| US-20070249625-A1 | Il-8 Receptor Antagonists | SMITHKLINE BEECHAM CORPORATION | 2007-10-25 | — | — | US | disclosed |
| US-20060040952-A1 | Il-8 receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2006-02-23 | — | — | US | disclosed |
| EP-1558259-A2 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004039775-A2 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040952-A1 | Il-8 receptor antagonists | CXCL8, CCR8, IL1RN | CXCR2 9/4885 |
| US-20070249625-A1 | Il-8 Receptor Antagonists | CXCL8, CCR8, IL1RN | CXCR2 9/4885 |
| US-20090093492-A1 | IL-8 RECEPTOR ANTAGONISTS | CXCL8, CCR8, IL1RN | CXCR2 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.