Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL159499 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL3664673 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL1985568 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL170557 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL10332456 | 1.00 | TDP1 (0.91) | — | |
| Propylene Glycol SCHEMBL5051858 | 1.00 | TDP1 (0.91) | — | |
| Propylene Glycol SCHEMBL1988316 | 0.96 | — | — | |
| Propylene Glycol SCHEMBL29058944 | 0.96 | — | — | |
| Propylene Glycol SCHEMBL11140327 | 0.96 | — | — | |
| Propylene Glycol SCHEMBL28330090 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315124-B1 | BILAYER TABLET FORMULATIONS | ASTRAZENECA AB (SE) | 2021-01-06 | — | — | EP | claimed |
| EP-2670397-B1 | PHARMACEUTICAL FORMULATIONS INCLUDING AN AMINE COMPOUND | BRISTOL MYERS SQUIBB CO (US) | 2020-05-13 | — | — | EP | claimed |
| CN-105193761-B | Bilayer tablet | 阿斯利康(瑞典)有限公司 | 2019-12-06 | — | — | CN | claimed |
| CN-108516966-A | Crystal form of Dapagliflozin and its preparation method and application | 浙江海正药业股份有限公司 | 2018-09-11 | — | — | CN | claimed |
| WO-2018142422-A1 | PROCESS FOR THE PREPARATION OF DAPAGLIFLOZIN | INDOCO REMEDIES LIMITED (IN) | 2018-08-09 | — | — | WO | claimed |
| EP-2498759-B1 | IMMEDIATE RELEASE TABLET FORMULATIONS | ASTRAZENECA AB (SE) | 2018-08-01 | — | — | EP | claimed |
| EP-2498758-B1 | BILAYER TABLET FORMULATIONS | ASTRAZENECA AB (SE) | 2018-07-25 | — | — | EP | claimed |
| EP-2611442-B1 | DRUG FORMULATIONS USING WATER SOLUBLE ANTIOXIDANTS | BRISTOL MYERS SQUIBB CO (US) | 2018-07-04 | — | — | EP | claimed |
| EP-3315124-A1 | BILAYER TABLET FORMULATIONS | Astrazeneca AB (SE) | 2018-05-02 | — | — | EP | claimed |
| US-20170333353-A1 | BILAYER TABLET FORMULATIONS | BRISTOL-MEYERS SQUIBB COMPANY | 2017-11-23 | — | — | US | claimed |
| US-20130129819-A1 | Pharmaceutical Formulations Containing An SGLT2 Inhibitor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-05-23 | — | — | US | claimed |
| US-20130034606-A1 | IMMEDIATE RELEASE TABLET FORMULATIONS | ASTRAZENECA UK LIMITED (GB) | 2013-02-07 | — | — | US | claimed |
| US-20120282336-A1 | BILAYER TABLET FORMULATIONS | ASTRAZENECA UK LIMITED (GB) | 2012-11-08 | — | — | US | claimed |
| CN-102740839-A | Immediate release tablet | BRISTOL MYER SQUIBB COMPANY | 2012-10-17 | — | — | CN | claimed |
| CN-102711739-A | bilayer tablet | BRISTOL MYERS SQUIBB CO | 2012-10-03 | — | — | CN | claimed |
| EP-2498758-A2 | BILAYER TABLET FORMULATIONS | Bristol-Myers Squibb Company (US) | 2012-09-19 | — | — | EP | claimed |
| EP-2498759-A2 | IMMEDIATE RELEASE TABLET FORMULATIONS | Bristol-Myers Squibb Company (US) | 2012-09-19 | — | — | EP | claimed |
| WO-2012031124-A2 | DRUG FORMULATIONS USING WATER SOLUBLE ANTIOXIDANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-08 | — | — | WO | claimed |
| WO-2011060290-A2 | IMMEDIATE RELEASE TABLET FORMULATIONS | Bristol-Myer Squibb Company (US) | 2011-05-19 | — | — | WO | claimed |
| WO-2011060256-A2 | BILAYER TABLET FORMULATIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-19 | — | — | WO | claimed |