SCHEMBL1563035

SCHEMBL1563035

C(=Cc1ccc(C2NCc3ccccc32)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRCP P42785 5/20 0.46
GAA P10253 1/20 0.45
GID4 Q8IVV7 1/20 0.39
RECQL P46063 1/20 0.39
MEN1 O00255 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
KMT2A Q03164 1/20 0.38
CA1 P00915 1/20 0.38
MGLL Q99685 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
KDM1A O60341 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1563034 1.00 PRCP (0.46) PRCPGAAGID4RECQLMEN1
SCHEMBL1563824 0.86 PRCP (0.59) PRCPGAAGID4RECQLKDM1A
SCHEMBL1563826 0.86 PRCP (0.59) PRCPGAAGID4RECQLKDM1A
SCHEMBL8203499 0.85 CA1 (0.36) PRCPGAAMEN1CYP3A4CYP2D6
SCHEMBL8203494 0.85 CA1 (0.36) PRCPGAAMEN1CYP3A4CYP2D6
SCHEMBL1563924 0.82 GID4 (0.62) PRCPGID4CYP3A4CYP2D6SMN1; SMN2
SCHEMBL1563923 0.82 GID4 (0.62) PRCPGID4CYP3A4CYP2D6SMN1; SMN2
SCHEMBL6985456 0.81 PRCP (0.66) PRCPGAAGID4RECQLMEN1
SCHEMBL10974810 0.81 PRCP (0.45) PRCPGAAGID4RECQLMEN1
SCHEMBL6829614 0.80 TDP1 (0.37) PRCPGAAGID4RECQLCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1865051-B1 Bleaching compositions PROCTER & GAMBLE (US) 2019-03-20 EP disclosed
EP-0905223-B2 Self thickened bleaching compositions PROCTER & GAMBLE (US) 2011-04-06 EP disclosed
US-7427170-B2 Method and device for delivery and confinement of surface cleaning composition THE CLOROX COMPANY (US) 2008-09-23 US disclosed
EP-1551645-B1 METHOD AND DEVICE FOR DELIVERY AND CONFINEMEMT OF SURFACE CLEANING COMPOSITION CLOROX CO (US) 2008-07-02 EP disclosed
US-7320955-B2 Compositions comprising complexes of cyclodextrin and at least one laundry treatment active THE PROCTER & GAMBLE COMPANY (US) 2008-01-22 US disclosed
WO-2007141735-A1 BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2007-12-13 WO disclosed
US-20070287651-A1 Bleaching compositions THE PROCTER & GAMBLE COMPANY 2007-12-13 US disclosed
EP-1865051-A1 Bleaching compositions The Procter and Gamble Company (US) 2007-12-12 EP disclosed
EP-0905223-B1 Self thickened bleaching compositions PROCTER & GAMBLE (US) 2007-04-25 EP disclosed
EP-1234014-B1 PROCESS FOR STABILISATION OF COLOURED BLEACHING COMPOSITIONS PROCTER & GAMBLE (US) 2007-01-03 EP disclosed
EP-0987313-A1 Bleaching compositions THE PROCTER & GAMBLE COMPANY (US) 2000-03-22 EP disclosed
EP-0987314-A1 Bleaching compositions THE PROCTER & GAMBLE COMPANY (US) 2000-03-22 EP disclosed
EP-0987315-A1 Bleaching compositions THE PROCTER & GAMBLE COMPANY (US) 2000-03-22 EP disclosed
WO-1999036497-A1 STABLE COLOURED THICKENED BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-07-22 WO disclosed
WO-1999015618-A1 STABLED THICKENED BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-04-01 WO disclosed
WO-1999015617-A1 BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-04-01 WO disclosed
EP-0905224-A1 Bleaching compositions THE PROCTER & GAMBLE COMPANY (US) 1999-03-31 EP disclosed
EP-0905223-A1 Self thickened bleaching compositions THE PROCTER & GAMBLE COMPANY (US) 1999-03-31 EP disclosed
WO-1999014305-A1 STABLE BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
EP-0903403-A1 Stable bleaching compositions THE PROCTER & GAMBLE COMPANY (US) 1999-03-24 EP disclosed