SCHEMBL15632207

SCHEMBL15632207

c1ccc(-n2ccc3ccc4c5ccccc5n(-c5cncc(-n6c7ccccc7c7ccc8ccn(-c9ccccc9)c8c76)c5)c4c32)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KDM4C Q9H3R0 1/20 0.33
IDO1 P14902 1/20 0.33
ALOX12 P18054 1/20 0.32
HTT P42858 2/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32
POLB P06746 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
DUSP3 P51452 1/20 0.32
FGFR1 P11362 1/20 0.31
TERT O14746 1/20 0.31
MAPK1 P28482 1/20 0.31
BIRC5 O15392 1/20 0.31
ALDH1A1 P00352 2/20 0.30
KMT2A Q03164 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15632219 0.89 KDM4E (0.43) KDM4EATML3MBTL1HTTPOLB
SCHEMBL17015389 0.88 KDM4E (0.46) KDM4EATML3MBTL1HTTPOLB
SCHEMBL15213666 0.88 KDM4E (0.52) KDM4EATML3MBTL1HTTPOLB
SCHEMBL15632358 0.87 KDM4E (0.39) KDM4EATML3MBTL1KDM4CIDO1
SCHEMBL15631987 0.86 KDM4E (0.50) KDM4EATML3MBTL1HTTPOLB
SCHEMBL16357306 0.85 KDM4E (0.53) KDM4EATML3MBTL1HTTPOLB
SCHEMBL16357583 0.85 KDM4E (0.53) KDM4EATML3MBTL1HTTPOLB
SCHEMBL16357326 0.85 KDM4E (0.37) KDM4EATML3MBTL1IDO1HTT
SCHEMBL10029941 0.85 L3MBTL1 (0.55) KDM4EATML3MBTL1HTTPOLB
SCHEMBL15632075 0.85 L3MBTL1 (0.39) KDM4EATML3MBTL1HTTBIRC5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014046392-A1 ORGANIC COMPOUND AND ELECTROLUMINESCENT ELEMENT HAVING SAME 주식회사 두산 (KR) 2014-03-27 WO disclosed