Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563552 | 1.00 | ALDH1A1 (0.51) | ALDH1A1CYP1A2CYP2C19LMNAGAA | |
| SCHEMBL1563010 | 1.00 | ALDH1A1 (0.51) | ALDH1A1CYP1A2CYP2C19LMNAGAA | |
| SCHEMBL1563013 | 1.00 | ALDH1A1 (0.51) | ALDH1A1CYP1A2CYP2C19LMNAGAA | |
| SCHEMBL1563688 | 0.81 | HPGD (0.47) | ALDH1A1CYP1A2CYP2C19LMNAGAA | |
| SCHEMBL1562776 | 0.81 | HPGD (0.47) | ALDH1A1CYP1A2CYP2C19LMNAGAA | |
| SCHEMBL1562771 | 0.81 | HPGD (0.47) | ALDH1A1CYP1A2CYP2C19LMNAGAA | |
| SCHEMBL1563681 | 0.81 | HPGD (0.47) | ALDH1A1CYP1A2CYP2C19LMNAGAA | |
| SCHEMBL1562940 | 0.70 | ATM (0.75) | ALDH1A1CYP1A2CYP2C19LMNAGAA | |
| SCHEMBL1562939 | 0.70 | ATM (0.75) | ALDH1A1CYP1A2CYP2C19LMNAGAA | |
| SCHEMBL6638156 | 0.70 | ATM (0.75) | ALDH1A1CYP1A2CYP2C19LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1475408-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM | BRIDGESTONE CORP (JP) | 2011-04-06 | — | — | EP | disclosed |
| US-20050176858-A1 | Rubber composition and pneumatic tire made therefrom | BRIDGESTONE CORPORATION | 2005-08-11 | — | — | US | disclosed |
| EP-1475408-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM | Bridgestone Corporation (JP) | 2004-11-10 | — | — | EP | disclosed |