Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 12/20 | 0.54 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | CCKAR | P32238 | 2/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15635838 | 0.92 | CTSA (0.55) | CTSAALDH1A1THRBHPGDNPSR1 | |
| SCHEMBL2325361 | 0.92 | CTSA (0.55) | CTSAALDH1A1THRBHPGDNPSR1 | |
| SCHEMBL15636384 | 0.92 | CTSA (0.53) | CTSAMALT1EGLN2EGLN1CYP26A1 | |
| SCHEMBL15636099 | 0.91 | CTSA (0.55) | CTSAALDH1A1THRBHPGDNPSR1 | |
| SCHEMBL15637072 | 0.91 | CYP26A1 (0.50) | CTSAMALT1DHODHCCKARCYP26A1 | |
| SCHEMBL15636499 | 0.90 | EGLN2 (0.57) | CTSAEGLN2EGLN1CYP26A1 | |
| SCHEMBL15635964 | 0.90 | CTSA (0.54) | CTSADHODH | |
| SCHEMBL15635631 | 0.89 | CTSA (0.54) | CTSAMALT1EGLN2EGLN1CYP26A1 | |
| SCHEMBL15636227 | 0.89 | CTSA (0.54) | CTSAMALT1EGLN2EGLN1CYP26A1 | |
| SCHEMBL15636772 | 0.87 | CTSA (0.52) | CTSANPSR1RXFP1CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |