Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 16/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | APLNR | P35414 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15637555 | 0.93 | CTSA (0.48) | CTSAMMECYP3A4APLNR | |
| SCHEMBL15637363 | 0.91 | CTSA (0.53) | CTSAKMT2AMMECYP3A4 | |
| SCHEMBL15635964 | 0.91 | CTSA (0.54) | CTSAMMECYP3A4APLNR | |
| SCHEMBL2325361 | 0.90 | CTSA (0.55) | CTSAMMECYP3A4ALDH1A1THRB | |
| SCHEMBL15636592 | 0.90 | CTSA (0.52) | CTSAKMT2ANPSR1RXFP1APLNR | |
| SCHEMBL15635838 | 0.90 | CTSA (0.55) | CTSAMMECYP3A4ALDH1A1THRB | |
| SCHEMBL15636099 | 0.90 | CTSA (0.55) | CTSAALDH1A1THRBHPGDNPSR1 | |
| SCHEMBL15636448 | 0.90 | CTSA (0.56) | CTSA | |
| SCHEMBL15637565 | 0.89 | MMP12 (0.49) | CTSAKMT2A | |
| SCHEMBL15636487 | 0.88 | CTSA (0.46) | CTSAKMT2AMMECYP3A4APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |