Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.51 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.44 |
| ▸ | ITGAV | P06756 | 3/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | CTSA | P10619 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15636410 | 1.00 | SUCNR1 (0.51) | SUCNR1EGLN2EGLN1CYP26A1ITGB3 | |
| SCHEMBL15635750 | 0.92 | SUCNR1 (0.60) | SUCNR1EGLN2EGLN1CYP26A1ITGB3 | |
| SCHEMBL15636998 | 0.92 | SUCNR1 (0.48) | SUCNR1EGLN2EGLN1ITGB3ITGA2B | |
| SCHEMBL15636934 | 0.91 | SUCNR1 (0.56) | SUCNR1EGLN2EGLN1CYP26A1ITGB3 | |
| SCHEMBL15637535 | 0.90 | SUCNR1 (0.48) | SUCNR1EGLN2EGLN1CYP26A1ITGB3 | |
| SCHEMBL15636937 | 0.88 | CTSA (0.53) | SUCNR1EGLN2EGLN1ITGB3ITGAV | |
| SCHEMBL15637544 | 0.88 | SUCNR1 (0.51) | SUCNR1EGLN2EGLN1CYP26A1ITGB3 | |
| SCHEMBL15636639 | 0.88 | CTSA (0.51) | SUCNR1EGLN2EGLN1CYP26A1MMP3 | |
| SCHEMBL15636981 | 0.85 | SUCNR1 (0.45) | SUCNR1EGLN2EGLN1ITGB3ITGAV | |
| SCHEMBL15636728 | 0.85 | CTSA (0.45) | SUCNR1EGLN2EGLN1CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |