Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 14/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | MME | P08473 | 2/20 | 0.53 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15636874 | 0.91 | CTSA (0.59) | CTSACYP3A4MME | |
| SCHEMBL15636981 | 0.91 | SUCNR1 (0.45) | CTSACYP3A4MMESUCNR1EGLN2 | |
| SCHEMBL15637544 | 0.89 | SUCNR1 (0.51) | CTSASUCNR1EGLN2EGLN1ITGB3 | |
| SCHEMBL15636410 | 0.88 | SUCNR1 (0.51) | CTSASUCNR1EGLN2EGLN1ITGB3 | |
| SCHEMBL15636731 | 0.88 | SUCNR1 (0.51) | CTSASUCNR1EGLN2EGLN1ITGB3 | |
| SCHEMBL15637065 | 0.87 | CTSA (0.60) | CTSACYP3A4MME | |
| SCHEMBL15636998 | 0.87 | SUCNR1 (0.48) | CTSASUCNR1EGLN2EGLN1TP53 | |
| SCHEMBL15635786 | 0.86 | CTSA (0.57) | CTSACYP3A4MME | |
| SCHEMBL15637074 | 0.85 | CTSA (0.56) | CTSACYP3A4MME | |
| SCHEMBL15637535 | 0.85 | SUCNR1 (0.48) | CTSASUCNR1EGLN2EGLN1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |