SCHEMBL15636749

SCHEMBL15636749

Fc1[c]cccc1-c1c(F)cccc1F

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
PDK2 Q15119 1/20 0.34
TTR P02766 1/20 0.31
AKR1A1 P14550 1/20 0.30
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17514577 0.83
SCHEMBL17514909 0.80
SCHEMBL17514504 0.80 NFE2L2 (0.32)
SCHEMBL434572 0.80 NOTUM (0.35)
SCHEMBL4709982 0.80
SCHEMBL2053601 0.79 CA1 (0.35) CA1CA2CA7CA9PDK2
SCHEMBL15637255 0.79 CA1 (0.39) CA1CA2CA7CA9PDK2
SCHEMBL15637380 0.79 CA1 (0.35) CA1CA2CA7CA9PDK2
SCHEMBL17144788 0.79 CA1 (0.35) CA1CA2CA7CA9PDK2
SCHEMBL2050891 0.79 CA1 (0.35) CA1CA2CA7CA9PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2903440-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES Bayer CropScience AG (DE) 2015-08-12 EP disclosed
WO-2014053450-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2014-04-10 WO disclosed