Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 17/20 | 0.49 |
| ▸ | CCR1 | P32246 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15636470 | 0.92 | CTSA (0.49) | CTSACYP3A4MME | |
| SCHEMBL15635846 | 0.89 | CTSA (0.49) | CTSACCR1CYP3A4MME | |
| SCHEMBL15635451 | 0.89 | CTSA (0.52) | CTSA | |
| SCHEMBL16223822 | 0.89 | CTSA (0.48) | CTSA | |
| SCHEMBL15636919 | 0.88 | CTSA (0.54) | CTSACYP3A4MME | |
| SCHEMBL15636909 | 0.86 | CTSA (0.56) | CTSACYP3A4MME | |
| SCHEMBL15637163 | 0.86 | CTSA (0.56) | CTSACYP3A4MME | |
| SCHEMBL15636472 | 0.85 | CTSA (0.55) | CTSACYP3A4MME | |
| SCHEMBL15636181 | 0.85 | CTSA (0.56) | CTSACYP3A4MME | |
| SCHEMBL15637664 | 0.85 | CTSA (0.49) | CTSACCR1CYP3A4MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2826772-A1 | Intermediates for the synthesis of oxygen-substituted 3-heteroaroylamino-propionic acid derivatives | SANOFI (FR) | 2015-01-21 | — | — | EP | disclosed |
| EP-2528902-B1 | OXYGEN-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2014-11-12 | — | — | EP | disclosed |
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |