Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 15/20 | 0.49 |
| ▸ | CCR1 | P32246 | 3/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15636470 | 0.93 | CTSA (0.49) | CTSAMMECYP3A4 | |
| SCHEMBL15636032 | 0.88 | CTSA (0.55) | CTSA | |
| SCHEMBL15636975 | 0.88 | CTSA (0.55) | CTSA | |
| SCHEMBL15636493 | 0.88 | CTSA (0.54) | CTSAMMECYP3A4 | |
| SCHEMBL15636245 | 0.86 | CTSA (0.47) | CTSACCR1MMECYP3A4KDM4E | |
| SCHEMBL15636181 | 0.86 | CTSA (0.56) | CTSAMMECYP3A4 | |
| SCHEMBL15636341 | 0.85 | CTSA (0.51) | CTSAMMECYP3A4 | |
| SCHEMBL15636817 | 0.85 | CTSA (0.49) | CTSACCR1MMECYP3A4 | |
| SCHEMBL15635846 | 0.84 | CTSA (0.49) | CTSACCR1MMECYP3A4 | |
| SCHEMBL15636673 | 0.84 | CTSA (0.52) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |