Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 3/20 | 0.53 |
| ▸ | CTSA | P10619 | 8/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15636824 | 1.00 | CYP26A1 (0.53) | CYP26A1CTSACYP3A4MMEDHODH | |
| SCHEMBL15637030 | 0.92 | CYP26A1 (0.50) | CYP26A1CTSACYP3A4MME | |
| SCHEMBL15637072 | 0.92 | CYP26A1 (0.50) | CYP26A1CTSACYP3A4MMEDHODH | |
| SCHEMBL15637420 | 0.92 | APLNR (0.54) | CYP26A1CTSACYP3A4MMEDHODH | |
| SCHEMBL15637555 | 0.91 | CTSA (0.48) | CYP26A1CTSACYP3A4MME | |
| SCHEMBL15635838 | 0.91 | CTSA (0.55) | CYP26A1CTSACYP3A4MMEDHODH | |
| SCHEMBL2325361 | 0.91 | CTSA (0.55) | CYP26A1CTSACYP3A4MMEDHODH | |
| SCHEMBL15635445 | 0.89 | CYP26A1 (0.49) | CYP26A1CTSACYP3A4MMEDHODH | |
| SCHEMBL15636457 | 0.89 | CTSA (0.63) | CTSACYP3A4MMEPTGS2 | |
| SCHEMBL15637180 | 0.89 | CTSA (0.52) | CYP26A1CTSACYP3A4MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |