Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 3/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14893179 | 0.88 | PTPRC (0.42) | PTPRCPTPN1ACMSDBACE1TRPA1 | |
| SCHEMBL15636571 | 0.86 | PGR (0.36) | PTPRCPTPN1ACMSDBACE1MAP4K4 | |
| SCHEMBL434573 | 0.81 | PTPRC (0.46) | PTPRCPTPN1ACMSDBACE1TRPA1 | |
| SCHEMBL15637656 | 0.80 | TTR (0.44) | ACMSDALOX5APFEN1PIK3R1PIK3CA | |
| SCHEMBL15637381 | 0.79 | TTR (0.35) | TRPA1ALOX5APFEN1 | |
| SCHEMBL15637320 | 0.79 | ESR1 (0.32) | — | |
| SCHEMBL15637809 | 0.79 | KDM4E (0.38) | ALDH1A1L3MBTL1SMN1; SMN2GABRA1GABRG2 | |
| SCHEMBL29201471 | 0.79 | FASN (0.32) | — | |
| SCHEMBL2015544 | 0.78 | PTPRC (0.43) | PTPRCPTPN1ACMSDBACE1TRPA1 | |
| SCHEMBL15638352 | 0.78 | MCL1 (0.42) | BACE1TRPA1PDK2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903440-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | Bayer CropScience AG (DE) | 2015-08-12 | — | — | EP | disclosed |
| WO-2014053450-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-04-10 | — | — | WO | disclosed |