SCHEMBL15637643

SCHEMBL15637643

Fc1cccc(F)c1-c1cc[c]c(C(F)F)c1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.35
FEN1 P39748 1/20 0.35
TTR P02766 1/20 0.33
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15637381 0.78 TTR (0.35) ALOX5APFEN1TTRTRPA1
SCHEMBL15636751 0.77 TTR (0.37) ALOX5APFEN1TTRTRPA1
SCHEMBL15637710 0.75 ALOX5AP (0.33) ALOX5APFEN1TTR
SCHEMBL2053603 0.74 TTR (0.35) ALOX5APFEN1TTRTRPA1
SCHEMBL17144789 0.74 TTR (0.35) ALOX5APFEN1TTRTRPA1
SCHEMBL2050893 0.74 TTR (0.35) ALOX5APFEN1TTRTRPA1
SCHEMBL15637256 0.74 TTR (0.39) ALOX5APFEN1TTRTRPA1
SCHEMBL2053032 0.71 TRPA1 (0.38) ALOX5APFEN1TTRTRPA1
SCHEMBL15637319 0.70 ERN1 (0.33) ALOX5APFEN1TTR
SCHEMBL15637148 0.70 CUL4A (0.33) ALOX5APFEN1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2903440-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES Bayer CropScience AG (DE) 2015-08-12 EP disclosed
WO-2014053450-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2014-04-10 WO disclosed