Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 9/20 | 0.55 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.47 |
| ▸ | DCAF1 | Q9Y4B6 | 2/20 | 0.47 |
| ▸ | APLNR | P35414 | 3/20 | 0.47 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15636220 | 1.00 | CTSA (0.55) | CTSACYP26A1DCAF1APLNREGLN2 | |
| SCHEMBL15636828 | 0.93 | CTSA (0.55) | CTSACYP26A1DCAF1EGLN2EGLN1 | |
| SCHEMBL15637386 | 0.92 | CTSA (0.58) | CTSACYP26A1DCAF1EGLN2EGLN1 | |
| SCHEMBL15636740 | 0.92 | CTSA (0.58) | CTSACYP26A1DCAF1EGLN2EGLN1 | |
| SCHEMBL15636402 | 0.91 | CTSA (0.55) | CTSACYP26A1DCAF1EGLN2EGLN1 | |
| SCHEMBL15636539 | 0.91 | CTSA (0.55) | CTSACYP26A1DCAF1EGLN2EGLN1 | |
| SCHEMBL15635967 | 0.91 | CTSA (0.53) | CTSACYP26A1APLNR | |
| SCHEMBL15635375 | 0.91 | CTSA (0.55) | CTSACYP26A1APLNRPTGS2 | |
| SCHEMBL15635977 | 0.91 | CTSA (0.57) | CTSACYP26A1DCAF1EGLN2EGLN1 | |
| SCHEMBL15636694 | 0.91 | CTSA (0.57) | CTSACYP26A1DCAF1EGLN2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |