Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 15/20 | 0.53 |
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.45 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15637046 | 0.97 | CTSA (0.52) | CTSAPRNPNPSR1RXFP1CYP26A1 | |
| SCHEMBL15636592 | 0.92 | CTSA (0.52) | CTSAPRNPNPSR1RXFP1APLNR | |
| SCHEMBL15637409 | 0.91 | CTSA (0.55) | CTSACYP26A1 | |
| SCHEMBL15635626 | 0.91 | CTSA (0.52) | CTSACYP26A1 | |
| SCHEMBL15637684 | 0.91 | CTSA (0.55) | CTSACYP26A1APLNR | |
| SCHEMBL15636220 | 0.91 | CTSA (0.55) | CTSACYP26A1APLNR | |
| SCHEMBL15636772 | 0.91 | CTSA (0.52) | CTSAPRNPNPSR1RXFP1CYP26A1 | |
| SCHEMBL15636942 | 0.91 | CTSA (0.52) | CTSAPRNPNPSR1RXFP1CYP26A1 | |
| SCHEMBL15635884 | 0.91 | CTSA (0.52) | CTSAPRNPNPSR1RXFP1CYP26A1 | |
| SCHEMBL15636640 | 0.91 | CTSA (0.52) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |