Sugi Predict

Sugi Predict / Compounds / SCHEMBL15639780

SCHEMBL15639780

SCHEMBL15639780

N#Cc1ccccc1-n1ccc(N)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.44
▸ LMNA P02545 1/20 0.37
▸ RPS6KB1 P23443 1/20 0.36
▸ ROCK1 Q13464 1/20 0.36
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ HIF1A Q16665 1/20 0.36
▸ MAPT P10636 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ TSHR P16473 2/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.34
▸ GAA P10253 1/20 0.34
▸ CYP19A1 P11511 1/20 0.34
▸ NPSR1 Q6W5P4 2/20 0.34
▸ HPGD P15428 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29572822 1.00 KDM4E (0.44) KDM4ELMNARPS6KB1ROCK1SMN1; SMN2
SCHEMBL26110316 0.83 KDM4E (0.44) KDM4ERPS6KB1ROCK1SMN1; SMN2HIF1A
SCHEMBL30506360 0.81 AR (0.34) KDM4ELMNASMN1; SMN2HIF1A
SCHEMBL27549526 0.79 KDM4E (0.55) KDM4ESMN1; SMN2HIF1AMAPTTSHR
SCHEMBL25023901 0.79 KDM4E (0.44) KDM4ELMNARPS6KB1ROCK1SMN1; SMN2
SCHEMBL10645685 0.79 HTT (0.35) KDM4ELMNAROCK1KMT2ACYP19A1
SCHEMBL15768092 0.76 KDM4E (0.48) KDM4ERPS6KB1ROCK1SMN1; SMN2HIF1A
SCHEMBL15638638 0.76 KDM4E (0.43) KDM4ESMN1; SMN2MAPTALDH1A1HPGD
SCHEMBL29473273 0.76 NPC1 (0.42) KDM4EMAPTCYP3A4NPSR1HTT
SCHEMBL30333162 0.76 KDM4E (0.44) KDM4ELMNASMN1; SMN2HIF1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11548854-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2023-01-10 — — US disclosed
US-11332448-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2022-05-17 — — US disclosed
CN-113243374-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2022-04-26 — — CN disclosed
CN-113243374-A Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2021-08-13 — — CN disclosed
CN-108477173-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2021-07-02 — — CN disclosed
US-10961201-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2021-03-30 — — US disclosed
US-20210053924-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2021-02-25 — — US disclosed
US-20210017136-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2021-01-21 — — US disclosed
US-10689348-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2020-06-23 — — US disclosed
US-10435374-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2019-10-08 — — US disclosed
CN-108477173-A Heterocyclic compound as insecticide 拜耳农作物科学股份公司 2018-09-04 — — CN disclosed
CN-105101800-B Heterocyclic Compounds as Pesticides 拜耳农作物科学股份公司 2018-04-13 — — CN disclosed
US-9802899-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2017-10-31 — — US disclosed
US-20170305864-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2017-10-26 — — US disclosed
EP-2903440-B1 HETEROCYCLIC COMPOUNDS AS PEST CONTROLLING AGENTS BAYER CROPSCIENCE AG (DE) 2017-09-06 — — EP disclosed
EP-2999338-B1 KNOWN AND NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2017-07-12 — — EP disclosed
CN-105101800-A Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG 2015-11-25 — — CN disclosed
US-20150239847-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2015-08-27 — — US disclosed
EP-2903440-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES Bayer CropScience AG (DE) 2015-08-12 — — EP disclosed
WO-2014053450-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2014-04-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10435374-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS KDM4E 1583/4885LMNA 1612/4885RPS6KB1 4210/4885
US-20170305864-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES DDT, ACHE, PTMS KDM4E 1583/4885LMNA 1612/4885RPS6KB1 4210/4885
US-10961201-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS KDM4E 1583/4885LMNA 1612/4885RPS6KB1 4210/4885
US-10689348-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS KDM4E 1583/4885LMNA 1612/4885RPS6KB1 4210/4885
US-11548854-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS KDM4E 1583/4885LMNA 1612/4885RPS6KB1 4210/4885
US-20210053924-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES DDT, ACHE, PTMS KDM4E 1583/4885LMNA 1612/4885RPS6KB1 4210/4885
US-11332448-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS KDM4E 1583/4885LMNA 1612/4885RPS6KB1 4210/4885
US-20210017136-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES DDT, ACHE, PTMS KDM4E 1583/4885LMNA 1612/4885RPS6KB1 4210/4885
US-20150239847-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES DDT, ACHE, PTMS KDM4E 1583/4885LMNA 1612/4885RPS6KB1 4210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.