Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 20/20 | 0.66 |
| ▸ | ROCK1 | Q13464 | 12/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15639810 | 0.89 | ROCK2 (0.84) | ROCK2ROCK1 | |
| SCHEMBL15639963 | 0.89 | ROCK2 (0.62) | ROCK2ROCK1 | |
| SCHEMBL17041185 | 0.80 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL32670276 | 0.80 | ROCK2 (0.73) | ROCK2ROCK1 | |
| SCHEMBL15639798 | 0.80 | ROCK2 (0.73) | ROCK2ROCK1 | |
| SCHEMBL23359399 | 0.79 | ROCK2 (0.66) | ROCK2ROCK1 | |
| SCHEMBL17040532 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL30599032 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL15639309 | 0.79 | ROCK2 (0.98) | ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL29575526 | 0.79 | ROCK2 (0.98) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015157556-A1 | TREATMENT OF GVHD | KADMON CORPORATION, LLC (US) | 2015-10-15 | — | — | WO | disclosed |
| EP-2903645-A2 | TREATMENT OF OCULAR DISORDERS | Kadmon Corporation, LLC (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2903618-A2 | RHO KINASE INHIBITORS | Kadmon Corporation, LLC (US) | 2015-08-12 | — | — | EP | disclosed |
| WO-2014055996-A2 | RHO KINASE INHIBITORS | KADMON CORPORATION, LLC (US) | 2014-04-10 | — | — | WO | disclosed |
| WO-2014055999-A2 | TREATMENT OF OCULAR DISORDERS | KADMON CORPORATION, LLC (US) | 2014-04-10 | — | — | WO | disclosed |