Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 9/20 | 0.58 |
| ▸ | SRC | P12931 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2058867 | 0.85 | FGFR1 (0.61) | FGFR1SRCHTTALDH1A1HPGD | |
| SCHEMBL19848656 | 0.76 | FGFR1 (0.76) | FGFR1SRCHTTALDH1A1HPGD | |
| SCHEMBL12822202 | 0.76 | FGFR1 (0.62) | FGFR1SRCHPGD | |
| SCHEMBL23846263 | 0.75 | FGFR1 (0.76) | FGFR1SRCHTTALDH1A1HPGD | |
| SCHEMBL20698049 | 0.74 | HTT (0.65) | FGFR1SRCHTTALDH1A1HPGD | |
| SCHEMBL19911376 | 0.73 | FGFR1 (1.00) | FGFR1SRCHTTALDH1A1HPGD | |
| SCHEMBL374942 | 0.73 | FGFR1 (0.61) | FGFR1SRCHTTALDH1A1HPGD | |
| SCHEMBL1580271 | 0.73 | HTT (0.79) | FGFR1HTT | |
| Sulfuric Acid SCHEMBL2295927 | 0.73 | HTT (0.79) | FGFR1HTT | |
| SCHEMBL13993884 | 0.73 | FGFR1 (0.76) | FGFR1SRCHTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8697739-B2 | Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof | NOVARTIS AG (CH) | 2014-04-15 | — | — | US | disclosed |