SCHEMBL2058867

SCHEMBL2058867

O=S(=O)(O)c1ccc2ncn(-c3ccccc3)c2c1

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 10/20 0.61
SRC P12931 3/20 0.55
HTT P42858 2/20 0.54
ALDH1A1 P00352 2/20 0.54
HPGD P15428 1/20 0.54
MAPK1 P28482 1/20 0.54
MAPK10 P53779 1/20 0.54
NCOA1 Q15788 1/20 0.54
NCOA3 Q9Y6Q9 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL374942 0.88 FGFR1 (0.61) FGFR1SRCHTTALDH1A1HPGD
Hydrochloric Acid SCHEMBL1276068 0.87 FGFR1 (0.60) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL15640935 0.85 FGFR1 (0.58) FGFR1SRCHTTALDH1A1HPGD
Sulfuric Acid SCHEMBL2295927 0.80 HTT (0.79) FGFR1HTT
SCHEMBL12730486 0.76 FGFR1 (0.76) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL13993884 0.76 FGFR1 (0.76) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL6227705 0.75 DYRK1A (0.45) HTTALDH1A1
Hydrochloric Acid SCHEMBL7990178 0.75 FGFR1 (0.73) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL23846263 0.75 FGFR1 (0.76) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL7079798 0.75 FGFR1 (0.41) FGFR1SRCALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6881415-B1 Emulsifier-free finely dispersed water-in-oil type systems BEIERSDORF AG (DE) 2005-04-19 US claimed
US-8425883-B2 Cosmetic sun protection product based on W/Si-emulsions COTY PRESTIGE LANCASTER GROUP GMBH (DE) 2013-04-23 US disclosed
US-7968129-B2 Cosmetic skin care complex with anti-aging effect COTY PRESTIGE LANCASTER GROUP GMBH (DE) 2011-06-28 US disclosed
CN-101484122-B Cosmetic preparation comprising an anti-aging skin care complex COTY PRESTIGE LANCASTER GROUP 2011-06-22 CN disclosed
US-7906158-B2 Moisture-regulating cosmetic COTY PRESTIGE LANCASTER GROUP GMBH (DE) 2011-03-15 US disclosed
CN-101048201-B Moisture-regulating cosmetic COTY PRESTIGE LANCASTER GROUP 2010-06-23 CN disclosed
US-20090311202-A1 COSMETIC PREPARATION FOR EXTENSION TANNING COTY PRESTIGE LANCASTER GROUP GMBH (DE) 2009-12-17 US disclosed
US-20090196895-A1 COSMETIC PREPARATION COMPRISING AN ANTI-AGING SKIN CARE COMPLEX JPMORGAN CHASE BANK, N.A. 2009-08-06 US disclosed
US-20090185989-A1 COSMETIC SUN PROTECTION PRODUCT BASED ON W/SI-EMULSIONS COTY PRESTIGE LANCASTER GROUP GMBH (DE) 2009-07-23 US disclosed
CN-101484122-A Cosmetic preparation comprising an anti-aging skin care complex COTY PRESTIGE LANCASTER GROUP (DE) 2009-07-15 CN disclosed
US-20070269400-A1 MOISTURE-REGULATING COSMETIC JPMORGAN CHASE BANK, N.A. 2007-11-22 US disclosed
CN-101048201-A Moisture-regulating cosmetic COTY PRESTIGE LANCASTER GROUP (DE) 2007-10-03 CN disclosed