SCHEMBL15645293

SCHEMBL15645293

COC(=O)C1C2C=CC(C1C(=O)O)C(C(=O)OC)C2C(=O)OC

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 5/20 0.48
PPM1B O75688 1/20 0.47
PTPN1 P18031 1/20 0.47
PPP1CC P36873 1/20 0.47
TDP1 Q9NUW8 3/20 0.46
CTDSP1 Q9GZU7 1/20 0.41
HTT P42858 2/20 0.37
ALDH1A1 P00352 1/20 0.37
GLA P06280 1/20 0.37
HPGD P15428 1/20 0.37
CYP2C19 P33261 1/20 0.36
APEX1 P27695 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
PKM P14618 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
TP53 P04637 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15645760 1.00 POLB (0.48) POLBPPM1BPTPN1PPP1CCTDP1
SCHEMBL5494856 1.00 POLB (0.48) POLBPPM1BPTPN1PPP1CCTDP1
SCHEMBL15645762 1.00 POLB (0.48) POLBPPM1BPTPN1PPP1CCTDP1
SCHEMBL11263569 0.91 CYP2C19 (0.41) POLBPPM1BPTPN1PPP1CCHTT
SCHEMBL3200631 0.86 POLB (0.70) POLBPPM1BPTPN1PPP1CCTDP1
SCHEMBL3215221 0.86 POLB (0.70) POLBPPM1BPTPN1PPP1CCTDP1
SCHEMBL389507 0.86 POLB (0.70) POLBPPM1BPTPN1PPP1CCTDP1
SCHEMBL8760765 0.86 POLB (0.70) POLBPPM1BPTPN1PPP1CCTDP1
SCHEMBL393414 0.86 POLB (0.70) POLBPPM1BPTPN1PPP1CCTDP1
SCHEMBL12636953 0.83 CYP2C19 (0.40) POLBPPM1BPTPN1PPP1CCHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2725067-B1 FLAMEPROOFED ALICYCLIC POLYIMIDE RESIN COMPOSITION AND THIN-WALLED MOLDED BODY OF SAME MITSUBISHI GAS CHEMICAL CO (JP) 2016-02-24 EP disclosed
EP-2725067-A1 FLAMEPROOFED ALICYCLIC POLYIMIDE RESIN COMPOSITION AND THIN-WALLED MOLDED BODY OF SAME Mitsubishi Gas Chemical Company, Inc. (JP) 2014-04-30 EP disclosed
US-20140114000-A1 FLAMEPROOFED ALICYCLIC POLYIMIDE RESIN COMPOSITION AND THIN-WALLED MOLDED BODY OF SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-04-24 US disclosed