Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29058094 | 1.00 | TSHR (0.53) | TSHRTHRBEPHX1CES2CES1 | |
| SCHEMBL15655397 | 1.00 | TSHR (0.53) | TSHRTHRBEPHX1CES2CES1 | |
| SCHEMBL1148089 | 1.00 | TSHR (0.53) | TSHRTHRBEPHX1CES2CES1 | |
| SCHEMBL30925357 | 1.00 | TSHR (0.53) | TSHRTHRBEPHX1CES2CES1 | |
| SCHEMBL15656588 | 1.00 | TSHR (0.53) | TSHRTHRBEPHX1CES2CES1 | |
| SCHEMBL15657098 | 1.00 | TSHR (0.53) | TSHRTHRBEPHX1CES2CES1 | |
| SCHEMBL5838475 | 1.00 | TSHR (0.53) | TSHRTHRBEPHX1CES2CES1 | |
| SCHEMBL15657093 | 1.00 | TSHR (0.53) | TSHRTHRBEPHX1CES2CES1 | |
| SCHEMBL15658064 | 1.00 | TSHR (0.53) | TSHRTHRBEPHX1CES2CES1 | |
| SCHEMBL15656743 | 1.00 | TSHR (0.53) | TSHRTHRBEPHX1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9061894-B2 | Method for forming microelectrode-pair arrays on silicon substrate surface with hydrophobic silicon pillars | INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-06-23 | — | — | US | disclosed |
| US-20140120271-A1 | METHOD FOR FORMING MICROELECTRODE-PAIR ARRAYS ON SILICON SUBSTRATE SURFACE WITH HYDROPHOBIC SILICON PILLARS | INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2014-05-01 | — | — | US | disclosed |