Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15663486 | 0.86 | PDE10A (0.51) | PDE10A | |
| SCHEMBL15663440 | 0.76 | GRM5 (0.49) | PDE10A | |
| SCHEMBL15663568 | 0.76 | PDE10A (0.40) | PDE10A | |
| SCHEMBL5207920 | 0.75 | PDE10A (0.51) | PDE10AACSS2 | |
| SCHEMBL15664015 | 0.75 | PDE10A (0.41) | PDE10A | |
| SCHEMBL15663452 | 0.74 | GRM5 (0.52) | PDE10A | |
| SCHEMBL15663531 | 0.74 | PDE10A (0.40) | PDE10A | |
| SCHEMBL2826935 | 0.74 | GRM5 (0.46) | ACSS2 | |
| SCHEMBL15663798 | 0.74 | NPC1 (0.44) | PDE10A | |
| SCHEMBL15663956 | 0.74 | PDE10A (0.38) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858854-B1 | PYRIDINE-2-CARBOXAMIDE DERIVATIVES AS MGLUR5 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2014-05-07 | — | — | EP | claimed |