SCHEMBL15664316

SCHEMBL15664316

Nc1ccc(CCCCCCSS(=O)(=O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.47
RECQL P46063 1/20 0.43
CA2 P00918 4/20 0.42
GFER P55789 1/20 0.42
MGLL Q99685 2/20 0.39
S1PR2 O95136 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38
MAOA P21397 2/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
NT5E P21589 1/20 0.37
HTR2A P28223 1/20 0.37
CYP19A1 P11511 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15665189 1.00 MAOB (0.47) MAOBRECQLCA2GFERMGLL
SCHEMBL15665038 0.98 MAOB (0.48) MAOBRECQLCA2GFERMGLL
SCHEMBL15665045 0.93 RECQL (0.46) MAOBRECQLCA2GFERMAOA
SCHEMBL3245281 0.86 RECQL (0.48) MAOBRECQLCA2GFERMAOA
SCHEMBL15664453 0.83 MAOA (0.46) MAOBCA2MGLLMAOAALDH1A1
SCHEMBL15665350 0.83 MAOA (0.46) MAOBCA2MGLLMAOAALDH1A1
SCHEMBL15665053 0.81 MAOB (0.47) MAOBCA2MGLLMAOAALDH1A1
SCHEMBL5336202 0.77 MAOB (0.52) MAOBRECQLCA2GFERMGLL
SCHEMBL15664821 0.75 MAOA (0.49) MAOBCA2MGLLMAOAALDH1A1
SCHEMBL4021564 0.75 MAOB (0.76) MAOBRECQLGFERMAOAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103804725-B Tyre element and manufacture method thereof 东洋橡胶工业株式会社 2016-10-26 CN disclosed
CN-103804723-B Tyre element and preparation method thereof 东洋橡胶工业株式会社 2016-09-07 CN disclosed
US-8946325-B2 Tire member and method for manufacturing the same TOYO TIRE & RUBBER CO., LTD. (JP) 2015-02-03 US disclosed
CN-103804723-A Tire member and method for manufacturing the same TOYO TIRE & RUBBER CO 2014-05-21 CN disclosed
CN-103804725-A Tire member and method for manufacturing the same TOYO TIRE & RUBBER CO 2014-05-21 CN disclosed
US-20140128525-A1 TIRE MEMBER AND METHOD FOR MANUFACTURING THE SAME TOYO TIRE & RUBBER CO., LTD. (JP) 2014-05-08 US disclosed
US-20140128498-A1 TIRE MEMBER AND METHOD FOR MANUFACTURING THE SAME TOYO TIRE & RUBBER CO., LTD. (JP) 2014-05-08 US disclosed