SCHEMBL15664889

SCHEMBL15664889

CCCCCCCCCCCCCCCCCC[C@H](C)[C@H](CCCCCCCCCCCCCCCC[C@H](C)C1C[C@H]1CCCCCCCCC=CCCCCCCCC[C@@H](O[Si](C)(C)C(C)(C)C)C(CCCCCCCCCCCCCCCCCCCCCCCCOC(=O)C(C)(C)C)C(=O)OC)OC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.32
PRKCE Q02156 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15664887 1.00 PRKCA (0.32) PRKCAPRKCE
SCHEMBL15664548 0.94 EPHX2 (0.31)
SCHEMBL15664547 0.94 EPHX2 (0.31)
SCHEMBL15667724 0.90 ZDHHC7 (0.30)
SCHEMBL15679449 0.90 ZDHHC7 (0.30)
SCHEMBL15679445 0.88 PRKCA (0.32) PRKCAPRKCE
SCHEMBL15664427 0.87
SCHEMBL15665051 0.84 PRKCA (0.35) PRKCAPRKCE
SCHEMBL15665049 0.84 PRKCA (0.35) PRKCAPRKCE
SCHEMBL15665047 0.84 PRKCA (0.35) PRKCAPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9945852-B2 Method for determining the presence or absence of a biomarker ARCIS BIOTECHNOLOGY HOLDINGS LIMITED (GB) 2018-04-17 US disclosed
EP-2705367-B1 METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER BANGOR UNIV (GB) 2017-04-26 EP disclosed
US-20140127709-A1 METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER BANGOR UNIVERSITY (GB) 2014-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140127709-A1 METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER CA14, CD63, CA12 PRKCA 4119/4885PRKCE 4056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.