Serine

Serine

SCHEMBL15670508

NC(CO)C(=O)O.Oc1ccco1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.42
PTGS1 P23219 3/20 0.42
PKM P14618 2/20 0.42
POLB P06746 1/20 0.42
PTPN1 P18031 1/20 0.42
PTPN7 P35236 1/20 0.42
BLM P54132 1/20 0.42
KMT2A Q03164 1/20 0.42
ESR2 Q92731 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALPI P09923 1/20 0.42
XIAP P98170 1/20 0.42
SLC1A3 P43003 2/20 0.41
SLC1A2 P43004 2/20 0.41
SLC1A1 P43005 2/20 0.41
CYP2C19 P33261 1/20 0.38
KIF11 P52732 3/20 0.37
KDM4E B2RXH2 2/20 0.37
HIF1A Q16665 2/20 0.37
TDP1 Q9NUW8 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serine SCHEMBL15670511 1.00 SLC7A5 (0.42) SLC7A5PTGS1PKMPOLBPTPN1
Cysteine SCHEMBL15670419 0.86 PTGS1 (0.55) SLC7A5PTGS1PKMPOLBPTPN1
Cysteine SCHEMBL15670416 0.86 PTGS1 (0.55) SLC7A5PTGS1PKMPOLBPTPN1
Aspartic Acid SCHEMBL15670472 0.85 MIF (0.43) SLC7A5PTGS1PKMPOLBPTPN1
Aspartic Acid SCHEMBL15670468 0.85 MIF (0.43) SLC7A5PTGS1PKMPOLBPTPN1
Asparagine SCHEMBL15670521 0.83 CYP2C19 (0.50) SLC7A5PTGS1PKMPOLBPTPN1
Cystine SCHEMBL15671139 0.83 KIF11 (0.42) SLC7A5PTGS1PKMPOLBPTPN1
Cystine SCHEMBL15671143 0.83 KIF11 (0.42) SLC7A5PTGS1PKMPOLBPTPN1
Asparagine SCHEMBL15670518 0.83 CYP2C19 (0.50) SLC7A5PTGS1PKMPOLBPTPN1
Dl-Phenylalanine SCHEMBL15670612 0.82 SLC7A5 (0.69) SLC7A5PTGS1PKMALPIXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2914131-A1 FLAVOUR ADDITIVES Mars, Incorporated (US) 2015-09-09 EP disclosed
WO-2014068044-A1 FLAVOUR ADDITIVES MARS, INCORPORATED (US) 2014-05-08 WO disclosed