Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 4/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 7/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1569191 | 0.85 | FYN (0.48) | FYNKDM5AKDM5BMBOAT4KLKB1 | |
| SCHEMBL1569159 | 0.82 | CHEK2 (0.47) | KDM5AKDM5BMBOAT4KLKB1MAP4K1 | |
| SCHEMBL1568328 | 0.82 | MBOAT4 (0.44) | FYNKDM5AKDM5BGPR52MBOAT4 | |
| SCHEMBL582010 | 0.82 | KDM5B (0.56) | FYNVNN1KDM5AKDM5BKLKB1 | |
| SCHEMBL1569175 | 0.82 | PARP1 (0.53) | KDM5AKDM5BGPR52MBOAT4KDM4C | |
| SCHEMBL1568231 | 0.79 | MBOAT4 (0.49) | KDM5AKDM5BMBOAT4KLKB1MAP4K1 | |
| SCHEMBL1568101 | 0.79 | MBOAT4 (0.44) | KDM5AKDM5BMBOAT4KLKB1MAP4K1 | |
| SCHEMBL1569193 | 0.79 | BRD4 (0.55) | FYNKDM5AKDM5BMBOAT4KDM4C | |
| SCHEMBL1569156 | 0.79 | CYP17A1 (0.55) | KDM5AKDM5BMBOAT4KLKB1MAP4K1 | |
| SCHEMBL1569142 | 0.79 | PARP1 (0.53) | VNN1KDM5AKDM5BMBOAT4KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307379-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2011-04-13 | — | — | EP | claimed |
| EP-2307379-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2011-04-13 | — | — | EP | disclosed |