Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.69 |
| ▸ | PNLIP | P16233 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489963 | 0.84 | PTGDR2 (0.50) | PTGDR2PNLIPNPC1RAB9APOLB | |
| SCHEMBL2492872 | 0.84 | PTGDR2 (0.50) | PTGDR2PNLIPNPC1RAB9APOLB | |
| SCHEMBL2489044 | 0.83 | PTGDR2 (0.49) | PTGDR2PNLIPNPC1RAB9APOLB | |
| SCHEMBL18628476 | 0.82 | PTGDR2 (0.62) | PTGDR2PNLIPNPC1RAB9A | |
| SCHEMBL1570352 | 0.82 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL2489819 | 0.81 | PTGDR2 (0.50) | PTGDR2NPC1RAB9A | |
| SCHEMBL15949571 | 0.81 | PTGDR2 (0.80) | PTGDR2 | |
| SCHEMBL2490235 | 0.80 | PTGDR2 (0.53) | PTGDR2 | |
| SCHEMBL2488127 | 0.80 | PTGDR2 (0.49) | PTGDR2POLB | |
| SCHEMBL2489986 | 0.80 | PTGDR2 (0.53) | PTGDR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307397-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |