Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2486854 | 0.93 | PTGDR2 (0.49) | PTGDR2NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL2489027 | 0.91 | DEGS1 (0.50) | PTGDR2NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL2489986 | 0.90 | PTGDR2 (0.53) | PTGDR2NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL2488127 | 0.89 | PTGDR2 (0.49) | PTGDR2 | |
| SCHEMBL2490235 | 0.87 | PTGDR2 (0.53) | PTGDR2 | |
| SCHEMBL2489044 | 0.86 | PTGDR2 (0.49) | PTGDR2NPC1RAB9A | |
| SCHEMBL2492872 | 0.85 | PTGDR2 (0.50) | PTGDR2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2492752 | 0.85 | PTGDR2 (0.56) | PTGDR2 | |
| SCHEMBL2489821 | 0.84 | PTGDR2 (0.69) | PTGDR2NPC1RAB9A | |
| SCHEMBL2489963 | 0.84 | PTGDR2 (0.50) | PTGDR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379535-A1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma Inc. (US) | 2011-10-26 | — | — | EP | disclosed |