Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17427757 | 0.83 | NOS3 (0.39) | SMN1; SMN2HTTKMT2AHSD17B10KDM4E | |
| SCHEMBL31145165 | 0.81 | KDM4E (0.46) | SMN1; SMN2HTTKMT2AHSD17B10KDM4E | |
| SCHEMBL2066694 | 0.81 | HTT (0.39) | SMN1; SMN2HTTKMT2AHSD17B10KDM4E | |
| SCHEMBL28166044 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2HTTKMT2AHSD17B10KDM4E | |
| SCHEMBL15004184 | 0.81 | KDM4E (0.46) | SMN1; SMN2HTTKMT2AHSD17B10KDM4E | |
| SCHEMBL22771018 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2HTTKMT2AHSD17B10KDM4E | |
| SCHEMBL30403001 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2HTTKMT2AHSD17B10KDM4E | |
| SCHEMBL25696363 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2HTTKMT2AHSD17B10KDM4E | |
| Methyl Alcohol SCHEMBL10757708 | 0.79 | NOS3 (0.37) | SMN1; SMN2HTTKMT2AHSD17B10KDM4E | |
| SCHEMBL22770976 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2HTTKMT2AHSD17B10S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3628669-A1 | NOVEL COMPOUNDS AS NADPH OXIDASE INHIBITORS | GenKyoTex Suisse SA (CH) | 2020-04-01 | — | — | EP | disclosed |
| WO-2014072930-A2 | FUSED PYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-05-15 | — | — | WO | disclosed |