Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1569967 | 0.92 | PTGDR2 (0.41) | PTGDR2ALOX15TAS1R3TAS1R1PTGER4 | |
| SCHEMBL28794474 | 0.90 | PTGDR2 (0.50) | PTGDR2 | |
| SCHEMBL1570262 | 0.88 | PTGDR2 (0.40) | PTGDR2KDM4EKMT2A | |
| SCHEMBL1570023 | 0.88 | PTGDR2 (0.52) | PTGDR2 | |
| SCHEMBL1570161 | 0.80 | PTGDR2 (0.40) | PTGDR2KDM4EKMT2A | |
| SCHEMBL1569827 | 0.80 | PTGDR2 (0.51) | PTGDR2 | |
| SCHEMBL1570066 | 0.79 | PTGDR2 (0.40) | PTGDR2KDM4EKMT2A | |
| SCHEMBL27833988 | 0.77 | PTGDR2 (0.48) | PTGDR2 | |
| SCHEMBL28791651 | 0.77 | PTGDR2 (0.62) | PTGDR2 | |
| SCHEMBL1569647 | 0.73 | PTGDR2 (0.57) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3144303-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma, Inc. (US) | 2017-03-22 | — | — | EP | disclosed |
| US-9556139-B2 | 6-substituted phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC. (US) | 2017-01-31 | — | — | US | disclosed |
| EP-2379535-B1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC (US) | 2016-06-15 | — | — | EP | disclosed |
| EP-2826774-B1 | Intermediates for 6-substituted phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC (US) | 2016-05-25 | — | — | EP | disclosed |
| US-20150232442-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2015-08-20 | — | — | US | disclosed |
| US-9096567-B2 | 6-substituted phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC. (US) | 2015-08-04 | — | — | US | disclosed |
| EP-2826774-A1 | Intermediates for 6-substituted phenoxychroman carboxylic acid derivatives | Array Biopharma, Inc. (US) | 2015-01-21 | — | — | EP | disclosed |
| EP-2307397-B1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC (US) | 2014-08-20 | — | — | EP | disclosed |
| US-20140221342-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2014-08-07 | — | — | US | disclosed |
| US-8785445-B2 | 7-phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8716498-B2 | 6-substituted phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA, INC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-20140005418-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2014-01-02 | — | — | US | disclosed |
| US-8569522-B2 | 6-substituted phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20120101103-A1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2012-04-26 | — | — | US | disclosed |
| EP-2379535-A1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma Inc. (US) | 2011-10-26 | — | — | EP | disclosed |
| US-20110105463-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2011-05-05 | — | — | US | disclosed |
| EP-2307397-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010075200-A1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| WO-2009158426-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221342-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | HRH1, HRH2, HRH4 | PTGDR2 705/4885ALOX15 764/4885TAS1R3 1447/4885 |
| US-20110105463-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | GPR52, CD22, CD4 | PTGDR2 13/4885ALOX15 4048/4885TAS1R3 2152/4885 |
| US-20150232442-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | GPR52, CD22, CD74 | PTGDR2 6/4885ALOX15 3659/4885TAS1R3 2313/4885 |
| US-20140005418-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | UGT1A6, UGT2B7, UGT1A7 | PTGDR2 956/4885ALOX15 3426/4885TAS1R3 4545/4885 |
| US-20120101103-A1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | PTGDR2, PTGDR, HRH2 | PTGDR2 1/4885ALOX15 208/4885TAS1R3 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.