Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5933377 | 0.85 | TDP1 (0.66) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2479873 | 0.81 | LMNA (0.59) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7228409 | 0.81 | MEN1 (0.61) | KMT2AMEN1NPC1RAB9ATDP1 | |
| SCHEMBL4796211 | 0.78 | KMT2A (0.54) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6359725 | 0.78 | TDP1 (0.58) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL4731326 | 0.78 | TDP1 (0.58) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL17687267 | 0.77 | TAAR1 (0.60) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1520363 | 0.77 | KMT2A (0.59) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28107769 | 0.77 | MEN1 (0.61) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2186353 | 0.76 | RCE1 (0.56) | KMT2AMEN1NPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307397-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009158426-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2009-12-30 | — | — | WO | disclosed |