⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15910175 | 0.87 | GABRR1 (0.46) | — | |
| SCHEMBL7932804 | 0.81 | TSHR (0.39) | — | |
| SCHEMBL156205 | 0.80 | — | — | |
| SCHEMBL15866578 | 0.80 | — | — | |
| SCHEMBL22780951 | 0.78 | HSD17B10 (0.44) | — | |
| SCHEMBL27966568 | 0.78 | — | — | |
| SCHEMBL21821254 | 0.78 | TP53 (0.33) | — | |
| SCHEMBL15701335 | 0.76 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL2439669 | 0.76 | GABRR1 (0.38) | — | |
| SCHEMBL15794330 | 0.76 | TP53 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170189369-A1 | MULTI-ARM POLYMERIC ALKANOATE CONJUGATES | NEKTAR THERAPEUTICS | 2017-07-06 | — | — | US | disclosed |
| US-9504755-B2 | Multi-arm polymeric alkanoate conjugates | NEKTAR THERAPEUTICS (US) | 2016-11-29 | — | — | US | disclosed |
| US-20160144045-A1 | MULTI-ARM POLYMERIC ALKANOATE CONJUGATES | NEKTAR THERAPEUTICS | 2016-05-26 | — | — | US | disclosed |
| US-9220790-B2 | Multi-arm polymeric alkanoate conjugates | NAKTAR THERAPEUTICS (US) | 2015-12-29 | — | — | US | disclosed |
| US-20150133534-A1 | MULTI-ARM POLYMERIC ALKANOATE CONJUGATES | NEKTAR THERAPEUTICS | 2015-05-14 | — | — | US | disclosed |
| US-8962566-B2 | Multi-arm polymeric alkanoate conjugates | NEKTAR THERAPEUTICS (US) | 2015-02-24 | — | — | US | disclosed |
| US-20140113961-A1 | MULTI-ARM POLYMERIC ALKANOATE CONJUGATES | NEKTAR THERAPEUTICS (US) | 2014-04-24 | — | — | US | disclosed |