SCHEMBL15701907

SCHEMBL15701907

CC(=O)CN(C)C(=O)c1ccccc1I

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.41
HPGD P15428 1/20 0.41
MEN1 O00255 3/20 0.40
ALDH1A1 P00352 2/20 0.40
TDP1 Q9NUW8 2/20 0.39
MAPT P10636 2/20 0.38
TP53 P04637 2/20 0.37
GAA P10253 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TSHR P16473 1/20 0.35
P2RX7 Q99572 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15701978 0.81 KMT2A (0.63) KMT2AHPGDMEN1ALDH1A1TDP1
SCHEMBL6361997 0.77 MEN1 (0.55) KMT2AHPGDMEN1ALDH1A1TDP1
SCHEMBL22317081 0.77 KMT2A (0.40) KMT2AHPGDMEN1ALDH1A1TDP1
SCHEMBL11225239 0.77 KMT2A (0.40) KMT2AHPGDMEN1ALDH1A1MAPT
SCHEMBL18919835 0.76 KMT2A (0.39) KMT2AHPGDMEN1ALDH1A1TDP1
SCHEMBL13337842 0.74 KMT2A (0.51) KMT2AHPGDMEN1ALDH1A1
SCHEMBL10488519 0.73 TP53 (0.53) HPGDALDH1A1TDP1MAPTTP53
SCHEMBL15702008 0.71 TPMT (0.42) HPGDALDH1A1SMN1; SMN2
SCHEMBL10013772 0.71 POLB (0.64) KMT2AMEN1TDP1
SCHEMBL31135393 0.71 MEN1 (0.41) KMT2AMEN1ALDH1A1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9278959-B2 Processes and reagents for making diaryliodonium salts NUTECH VENTURES (US) 2016-03-08 US disclosed
US-20140121371-A1 PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS Ground Fluor Pharmaceuticals, Inc. (US) 2014-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140121371-A1 PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS ABL1, ARSA, AADAC KMT2A 2400/4885HPGD 3858/4885MEN1 2793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.