Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PTPRF | P10586 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188296 | 0.84 | MEN1 (0.65) | MEN1KMT2ASMN1; SMN2KEAP1ALDH1A1 | |
| SCHEMBL7899919 | 0.82 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2KEAP1TDP1 | |
| SCHEMBL10013772 | 0.80 | POLB (0.64) | MEN1KMT2ATDP1KDM4EPOLB | |
| SCHEMBL31135393 | 0.80 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL11756196 | 0.79 | P2RX4 (0.49) | MEN1KMT2ASMN1; SMN2KEAP1TDP1 | |
| SCHEMBL10488519 | 0.78 | TP53 (0.53) | SMN1; SMN2KEAP1TDP1ALDH1A1MAPT | |
| SCHEMBL15701907 | 0.77 | KMT2A (0.41) | MEN1KMT2ASMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL18919835 | 0.77 | KMT2A (0.39) | MEN1KMT2ASMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL1018643 | 0.76 | ALDH1A1 (0.64) | MEN1KMT2ASMN1; SMN2KEAP1ALDH1A1 | |
| SCHEMBL354228 | 0.76 | KMT2A (0.59) | MEN1KMT2ASMN1; SMN2KEAP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382643-B | FeCl3Catalytic synthesis method of amide compounds | 中国人民解放军63975部队 | 2020-11-20 | — | — | CN | disclosed |
| WO-2017093544-A1 | ALKYNYL PHOSPHINE GOLD COMPLEXES FOR TREATING BACTERIAL INFECTIONS | AUSPHERIX LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |
| CN-106187803-A | The synthetic method of the amides compound that a kind of phosphorus oxychloride promotes | 中国人民解放军63975部队 | 2016-12-07 | — | — | CN | disclosed |
| CN-101208324-A | Benzo [ b ] furan and benzo [ b ] thiophene derivatives | LUNDBECK & CO AS H (DK) | 2008-06-25 | — | — | CN | disclosed |
| CN-1620434-A | Pyrrolidine-2-ones as factor Xa inhibitors | GLAXO GROUP LTD (GB) | 2005-05-25 | — | — | CN | disclosed |
| US-20050059726-A1 | Pyrrolidine-2-ones as factor xa inhibitors | GLAXO GROUP LIMITED (GB) | 2005-03-17 | — | — | US | disclosed |
| EP-1456172-A1 | PYRROLIDINE-2-ONES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053925-A1 | PYRROLIDINE-2-ONES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-07-03 | — | — | WO | disclosed |
| US-4279887-A | RADIOACTIVE SCANNING | MEDI-PHYSICS, INC. (US) | 1981-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059726-A1 | Pyrrolidine-2-ones as factor xa inhibitors | TFPI, F2, SERPINC1 | MEN1 1664/4885KMT2A 2900/4885SMN1; SMN2 2428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.