SCHEMBL15701965

SCHEMBL15701965

Cc1cc2[nH]cc(CCN(C)C)c2cc1C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 10/20 0.63
HTR1A P08908 8/20 0.63
HTR2C P28335 8/20 0.63
HTR1B P28222 8/20 0.63
HTR2A P28223 7/20 0.63
HTR2B P41595 6/20 0.63
HTR6 P50406 6/20 0.63
HTR3E A5X5Y0 4/20 0.63
HTR3B O95264 4/20 0.63
HTR1E P28566 4/20 0.63
HTR1F P30939 4/20 0.63
HTR7 P34969 4/20 0.63
HTR3A P46098 4/20 0.63
HTR5A P47898 4/20 0.63
HTR4 Q13639 4/20 0.63
HTR3D Q70Z44 4/20 0.63
HTR3C Q8WXA8 4/20 0.63
MPO P05164 1/20 0.60
SLC6A4 P31645 1/20 0.60
CYP1A2 P05177 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15701917 0.87 HTR1D (0.57) HTR1DHTR1AHTR2CHTR1BHTR2A
SCHEMBL15701953 0.86 HTR1D (0.56) HTR1DHTR1AHTR2CHTR1BHTR2A
SCHEMBL25747400 0.85 HTR1A (0.73) HTR1DHTR1AHTR2CHTR1BHTR2A
SCHEMBL30483760 0.85 HTR1A (0.73) HTR1DHTR1AHTR2CHTR1BHTR2A
SCHEMBL517481 0.81 HTR1D (0.61) HTR1DHTR1AHTR2CHTR1BHTR2A
SCHEMBL30483734 0.81 HTR1A (0.74) HTR1DHTR1AHTR2CHTR1BHTR2A
SCHEMBL25747532 0.81 HTR1A (0.74) HTR1DHTR1AHTR2CHTR1BHTR2A
SCHEMBL26203596 0.80 HTR1A (0.51) HTR1DHTR1AHTR2CHTR1BHTR2A
SCHEMBL15701982 0.80 HTR2A (0.70) HTR1DHTR1AHTR2CHTR1BHTR2A
SCHEMBL29633081 0.80 HTR1A (0.70) HTR1DHTR1AHTR2CHTR1BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9278959-B2 Processes and reagents for making diaryliodonium salts NUTECH VENTURES (US) 2016-03-08 US disclosed
US-20140121371-A1 PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS Ground Fluor Pharmaceuticals, Inc. (US) 2014-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140121371-A1 PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS ABL1, ARSA, AADAC HTR1D 3291/4885HTR1A 3821/4885HTR2C 2929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.