Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.56 |
| ▸ | CA1 | P00915 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 5/20 | 0.56 |
| ▸ | CA9 | Q16790 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TYMP | P19971 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 8/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28572545 | 1.00 | CA12 (0.56) | CA12CA1CA2CA9LMNA | |
| SCHEMBL28588942 | 1.00 | CA12 (0.56) | CA12CA1CA2CA9LMNA | |
| SCHEMBL17783197 | 1.00 | CA12 (0.56) | CA12CA1CA2CA9LMNA | |
| SCHEMBL4357511 | 0.98 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| SCHEMBL4360078 | 0.94 | CA12 (0.58) | CA12CA1CA2CA9LMNA | |
| Hydrochloric Acid SCHEMBL31250585 | 0.92 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| Trifluoroacetic Acid SCHEMBL29174409 | 0.88 | CA12 (0.46) | CA12CA1CA2CA9LMNA | |
| SCHEMBL8431954 | 0.87 | CA12 (0.61) | CA12CA1CA2CA9LMNA | |
| Trifluoroacetic Acid SCHEMBL29174403 | 0.87 | CA12 (0.47) | CA12CA1CA2CA9LMNA | |
| SCHEMBL15323854 | 0.86 | CA12 (0.54) | CA12CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116942615-A | Nanoparticle for co-delivering paclitaxel and gemcitabine as well as preparation method and application thereof | 湖南师范大学 | 2023-10-27 | — | — | CN | claimed |
| EP-3285750-B1 | GLUCOSE-RESPONSIVE INSULIN DELIVERY SYSTEM USING HYPOXIA-SENSITIVE NANOCOMPOSITES | UNIV NORTH CAROLINA STATE (US) | 2020-10-21 | — | — | EP | claimed |
| WO-2025133654-A1 | NEW CRYPTATE-TYPE (BICYCLIC) CHELATORS AND THEIR USE AS LIGANDS FOR MN(II)-BASED MRI CONTRAST AGENTS, 52MN-BASED PET DIAGNOSTIC AGENTS, AND 64/67CU(II)-ISOTOPE-BASED PET DIAGNOSTIC AND THERAPEUTIC AGENTS | DEBRECENI EGYETEM (HU) | 2025-06-26 | — | — | WO | disclosed |
| CN-116942615-A | Nanoparticle for co-delivering paclitaxel and gemcitabine as well as preparation method and application thereof | 湖南师范大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-113350489-A | Glucose responsive insulin delivery system using hypoxia sensitive nanocomposite material | 北卡罗来纳州立大学 | 2021-09-07 | — | — | CN | disclosed |
| CN-107530296-B | Glucose responsive insulin delivery system using hypoxia sensitive nanocomposite material | 北卡罗来纳州立大学 | 2021-06-22 | — | — | CN | disclosed |
| CN-108778248-A | METHODS AND COMPOSITIONS RELATED TO PHYSIOLOGICALLY RESPONSIVE MICRONEEDLE DELIVERY SYSTEMS | 北卡罗来纳州立大学 | 2018-11-09 | — | — | CN | disclosed |
| CN-108395489-A | A kind of 2- nitroimidazoles-cysteine-alginate material and preparation method thereof | 华侨大学 | 2018-08-14 | — | — | CN | disclosed |
| CN-107530296-A | Glucose responsive insulin delivery system using hypoxia sensitive nanocomposite material | 北卡罗来纳州立大学 | 2018-01-02 | — | — | CN | disclosed |
| US-9084806-B2 | Hypoxia-responsive nanoparticle for therapy and imaging of hypoxia-involving diseases | Research & Business Foundation Sungkyunkwan University (KR) | 2015-07-21 | — | — | US | disclosed |
| US-9084806-B2 | Hypoxia-responsive nanoparticle for therapy and imaging of hypoxia-involving diseases | Research & Business Foundation Sungkyunkwan University (KR) | 2015-07-21 | — | — | US | disclosed |
| US-9084806-B2 | Hypoxia-responsive nanoparticle for therapy and imaging of hypoxia-involving diseases | Research & Business Foundation Sungkyunkwan University (KR) | 2015-07-21 | — | — | US | disclosed |
| US-9044519-B2 | Radiotracer precursor for imaging of hypoxic tissue, radiotracer, and method for preparing the same | Atomic Energy Council—Institute of Nuclear Energy Research (TW) | 2015-06-02 | — | — | US | disclosed |
| US-20140371434-A1 | RADIOTRACER PRECURSOR FOR IMAGING OF HYPOXIC TISSUE, RADIOTRACER, AND METHOD FOR PREPARING THE SAME | ATOMIC ENERGY COUNCIL-INSTTITUTE OF NUCLEAR ENERGY RESEARCH (TW) | 2014-12-18 | — | — | US | disclosed |
| US-20140141084-A1 | HYPOXIA-RESPONSIVE NANOPARTICLE FOR THERAPY AND IMAGING OF HYPOXIA-INVOLVING DISEASES | Research & Business Foundation Sungkyunkwan University (KR) | 2014-05-22 | — | — | US | disclosed |
| US-20140141084-A1 | HYPOXIA-RESPONSIVE NANOPARTICLE FOR THERAPY AND IMAGING OF HYPOXIA-INVOLVING DISEASES | Research & Business Foundation Sungkyunkwan University (KR) | 2014-05-22 | — | — | US | disclosed |
| US-20140141084-A1 | HYPOXIA-RESPONSIVE NANOPARTICLE FOR THERAPY AND IMAGING OF HYPOXIA-INVOLVING DISEASES | Research & Business Foundation Sungkyunkwan University (KR) | 2014-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371434-A1 | RADIOTRACER PRECURSOR FOR IMAGING OF HYPOXIC TISSUE, RADIOTRACER, AND METHOD FOR PREPARING THE SAME | HIF1A, HIF1AN, HYOU1 | CA12 228/4885CA1 214/4885CA2 280/4885 |
| US-20140141084-A1 | HYPOXIA-RESPONSIVE NANOPARTICLE FOR THERAPY AND IMAGING OF HYPOXIA-INVOLVING DISEASES | HIF1A, HIF1AN, HYOU1 | CA12 14/4885CA1 41/4885CA2 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.