SCHEMBL15710456

SCHEMBL15710456

CCOC(=O)C(CCCN)C(=O)OCC

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CPB2 Q96IY4 2/20 0.53
▸ CYP1A2 P05177 1/20 0.52
▸ TDP1 Q9NUW8 4/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ L3MBTL1 Q9Y468 5/20 0.44
▸ MAPK1 P28482 3/20 0.44
▸ ALDH1A1 P00352 2/20 0.44
▸ TSHR P16473 1/20 0.44
▸ POLB P06746 1/20 0.44
▸ MAPT P10636 2/20 0.42
▸ CRHBP P24387 1/20 0.42
▸ CRHR2 Q13324 1/20 0.42
▸ ALOX15 P16050 1/20 0.41
▸ PTPN1 P18031 1/20 0.38
▸ MMP8 P22894 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17102907 0.94 CPB2 (0.61) CPB2CYP1A2TDP1MEN1KMT2A
SCHEMBL7940335 0.86 CPB2 (0.47) CPB2CYP1A2TDP1MEN1KMT2A
SCHEMBL11655565 0.86 TDP1 (0.56) CPB2TDP1MEN1KMT2AL3MBTL1
SCHEMBL7659602 0.86 TDP1 (0.56) CPB2TDP1MEN1KMT2AL3MBTL1
SCHEMBL6901399 0.84 TDP1 (0.55) CPB2TDP1MEN1KMT2AL3MBTL1
SCHEMBL21073906 0.84 TDP1 (0.55) CPB2TDP1MEN1KMT2AL3MBTL1
SCHEMBL1562155 0.83 TDP1 (0.50) CPB2CYP1A2TDP1MEN1KMT2A
SCHEMBL455720 0.82 TDP1 (0.53) TDP1MEN1KMT2AL3MBTL1MAPK1
SCHEMBL4613905 0.81 TDP1 (0.50) TDP1MEN1KMT2AL3MBTL1MAPK1
SCHEMBL7198274 0.81 CPB2 (0.51) CPB2CYP1A2ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2740738-B1 PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASE, PREPARATION METHODS AND USES THEREOF BEIJING FSWELCOME TECH DEVELOPMENT CO LTD (CN) 2018-03-28 — — EP disclosed
EP-2740738-B1 PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASE, PREPARATION METHODS AND USES THEREOF BEIJING FSWELCOME TECH DEVELOPMENT CO LTD (CN) 2018-03-28 — — EP disclosed
US-9138421-B2 Platinum compounds for treating cell proliferative diseases, preparation method and use thereof BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2015-09-22 — — US disclosed
US-9138421-B2 Platinum compounds for treating cell proliferative diseases, preparation method and use thereof BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2015-09-22 — — US disclosed
EP-2740738-A1 PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASE, PREPARATION METHODS AND USES THEREOF Beijing FSwelcome Technology Development Co., Ltd. (CN) 2014-06-11 — — EP disclosed
US-20140142079-A1 PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASES, PREPARATION METHOD AND USE THEREOF BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2014-05-22 — — US disclosed
US-20140142079-A1 PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASES, PREPARATION METHOD AND USE THEREOF BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2014-05-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140142079-A1 PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASES, PREPARATION METHOD AND USE THEREOF PCNA, POLI, MKI67 CPB2 2255/4885CYP1A2 4041/4885TDP1 2183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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