Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4550345 | 0.94 | KDM4E (0.49) | KDM4EATMCA2MAPTALDH1A1 | |
| SCHEMBL14244227 | 0.84 | TTR (0.49) | KDM4EATMCA2MAPTALDH1A1 | |
| SCHEMBL4550338 | 0.82 | ALDH1A1 (0.44) | KDM4EMAPTALDH1A1MEN1USP2 | |
| SCHEMBL10370856 | 0.81 | ATM (0.68) | KDM4EATMMEN1KMT2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL15351342 | 0.81 | ALDH1A1 (0.43) | KDM4EMAPTALDH1A1MEN1USP2 | |
| Hydrochloric Acid SCHEMBL30117172 | 0.81 | ALDH1A1 (0.43) | KDM4EMAPTALDH1A1MEN1USP2 | |
| SCHEMBL44393 | 0.80 | ATM (0.70) | KDM4EATMCA2ALDH1A1KMT2A | |
| SCHEMBL29535675 | 0.80 | ATM (0.70) | KDM4EATMCA2ALDH1A1KMT2A | |
| SCHEMBL19409880 | 0.80 | ATM (0.70) | KDM4EATMCA2ALDH1A1KMT2A | |
| SCHEMBL20679593 | 0.80 | MAPT (0.53) | KDM4EATMMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954684-B1 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2014-05-07 | — | — | EP | disclosed |