Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17195461 | 0.91 | DGAT1 (0.57) | DGAT1 | |
| SCHEMBL15690339 | 0.91 | DGAT1 (0.57) | DGAT1 | |
| SCHEMBL15711534 | 0.85 | DGAT1 (0.58) | DGAT1 | |
| SCHEMBL15711532 | 0.78 | DGAT1 (0.65) | DGAT1 | |
| SCHEMBL15690178 | 0.78 | DGAT1 (0.62) | DGAT1 | |
| SCHEMBL15689267 | 0.78 | DGAT1 (0.62) | DGAT1 | |
| SCHEMBL17195440 | 0.78 | DGAT1 (0.62) | DGAT1 | |
| SCHEMBL15711535 | 0.77 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL15689345 | 0.77 | DGAT1 (0.75) | DGAT1 | |
| SCHEMBL15690395 | 0.76 | DGAT1 (0.68) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014074761-A2 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2014-05-15 | — | — | WO | disclosed |